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IMPORTANT POINTS & DISCOVERIES
- The hemochorial placenta evolved early during mammalian evolution. This finding challenges the prevailing view that the hemochorial placentation is a ‘derived’, rather than an ancient form
- Galectins are key molecules that might participate in tolerance, especially during primate pregnancies
- The gene encoding the progesterone receptor has undergone adaptive changes during recent human evolution
- Unraveling of the relationships among placental mammals using phylogenomic methods
- Natural selection pressures are different in genes highly expressed in the prenatal when compared to those in the postnatal environments