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IMPORTANT POINTS & DISCOVERIES
- Neonatal and adult diseases often originate during early fetal development (e.g., cerebral palsy following fetal inflammatory response syndrome)
- Collaboration of highly specialized multi-disciplinary teams of investigators are needed to study the normal and aberrant developmental processes that unite with molecular, genetic, epigenetic and environmental factors during pregnancy/early fetal life and result in subsequent disease
- Understanding of disease mechanisms may lead to targeted interventions that improve subsequent health and survival free of impairment (e.g., therapeutic hypothermia for neonatal encephalopathy)