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RESEARCH QUESTIONS

  • Which cell-types define the different placental tissues during pregnancy? How are these genes expressed during gestation for each different cell-types?
  • What is the spatial distribution of the maternal and fetal cellular composition of the human placenta?
  • How do maternal and fetal immune cells interact with each other at the molecular level?
  • Which genes and cell-types are involved in the molecular mechanisms leading to a specific obstetrical syndrome (preterm birth, preeclampsia, fetal death, etc.)?
  • Which molecular mechanisms and genetic pathways underly genetic variants associated with pregnancy related phenotypes?