Cervical Pessary To Prevent Preterm Birth In Asymptomatic High-Risk Women: A Systematic Review And Meta-Analysis

Conde-Agudelo A, Romero R, Nicolaides KH.
Am J Obstet Gynecol. 2020 Feb 3. pii: S0002-9378(19)33085-6. doi: 10.1016/j.ajog.2019.12.266. [Epub ahead of print] Review.
PMID: 32027880

The placement of a cervical pessary did not reduce the risk of preterm birth (<37, <34, <32, and <28 weeks of gestation) or adverse perinatal outcomes in women with: a) Singleton gestations and a cervical length ≤25 mm; b) Unselected twin gestations; c) Twin gestations and a cervical length <38 mm; or d) twin gestations and a cervical length ≤25 mm. There were no significant differences in the risk of spontaneous preterm birth <34 weeks of gestation between pessary and vaginal progesterone in women with a singleton gestation and a cervical length ≤25 mm, and women with a twin gestation and a cervical length <38 mm.


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