Ewart Mark Haacke, Ph.D.
Academic Affiliations
  • Professor, Department of Radiology, Wayne State University School of Medicine
  • Professor and Vice-Chairman, Department of Biomedical Engineering, Wayne State University College of Engineering
  • Director of the Perinatal MR Imaging Research Program
Education and Training
  • PhD     University of Toronto, 1978 - High Energy Physics – Toronto, Ontario, Canada
  • MS      University of Toronto, 1975 - High Energy Physics – Toronto, Ontario, Canada
  • BSc     University of Toronto, 1973 - Math and Physics – Toronto, Ontario, Canada
Research Accomplishments
  • Pioneered MR angiographic imaging, fast imaging, and cardiovascular imaging
  • Developed a new method for imaging veins, micro-hemorrhaging, and iron called Susceptibility Weighted Imaging (SWI)
  • Pioneered the study of vascular effects in multiple sclerosis
  • Enhanced the use of iron/neuromelanin imaging as biomarkers of Parkinson’s disease
Research Interests
  • Imaging of the fetus, placenta, and maternal circulation
  • Vascular imaging of the human body using magnetic resonance imaging
  • Imaging of neurodegenerative diseases
Awards & Recognition
  • Gold Medal Award, International Society of Magnetic Resonance in Medicine, Kyoto, Japan
  • Silver Medal Award, Society of Magnetic Resonance
  • Gold Medal Award, International Society of Neurovascular Disease
Select Publications
  • Yadav BK, Hernandez-Andrade E, Krishnamurthy U, Buch S, Jella P, Trifan A, Yeo L, Hassan SS, Haacke EM, Romero R, Neelavalli J. Dual-imaging modality approach to evaluate cerebral hemodynamics in growth-restricted fetuses: oxygenation and perfusion. Fetal Diagn Ther. 2020 Feb; 47:145-155. PMID: 31434069.
  • Liu Y, Li J, He N, Chen Y, Jin Z, Yan F, Haacke EM. Optimizing neuromelanin contrast in the substantia nigra and locus coeruleus using a magnetization transfer contrast prepared 3D gradient recalled echo sequence. Neuroimage. 2020 Sep; 218:116935. PMID: 32413460. READ PUBLICATION
  • Buch S, Wang Y, Park MG, Jella PK, Hu J, Chen Y, Shah K, Ge Y, Haacke EM. Subvoxel vascular imaging of the midbrain using USPIO-Enhanced MRI. Neuroimage. 2020 Jun 29; 220:117106. Online ahead of print. PMID: 32615253. READ PUBLICATION
  • Cheng Z, He N, Huang P, Li Y, Tang R, Sethi SK, Ghassaban K, Yerramsetty KK, Palutla VK, Chen S, Yan F, Haacke EM. Imaging the Nigrosome 1 in the substantia nigra using susceptibility weighted imaging and quantitative susceptibility mapping: an application to Parkinson's disease. Neuroimage Clin. 2020; 25:102103. PMID: 31869769. READ PUBLICATION
  • Haacke EM, Chen Y, Utriainen D, Wu B, Wang Y, Xia S, He N, Zhang C, Wang X, Lagana MM, Luo Y, Fatemi A, Liu S, Gharabaghi S, Wu D, Sethi SK, Huang F, Sun T, Qu F, Yadav BK, Ma X, Bai Y, Wang M, Cheng J, Yan F. STrategically Acquired Gradient Echo (STAGE) imaging, part III: Technical advances and clinical applications of a rapid multi-contrast multi-parametric brain imaging method. Magn Reson Imaging. 2020 Jan; 65:15-26. PMID: 31629075. READ PUBLICATION
  • Yadav BK, Buch S, Krishnamurthy U, Jella P, Hernandez-Andrade E, Trifan A, Yeo L, Hassan SS, Mark Haacke E, Romero R, Neelavalli J. Quantitative susceptibility mapping in the human fetus to measure blood oxygenation in the superior sagittal sinus. Eur Radiol. 2019 Apr; 29:2017-2026. PMID: 30276673. READ PUBLICATION
  • Liu S, Utriainen D, Chai C, Chen Y, Wang L, Sethi SK, Xia S, Haacke EM.  Cerebral microbleed detection using Susceptibility Weighted Imaging and deep learning. Neuroimage. 2019:198:271-282. PMID: 31121296.
  • Ghassaban K, He N, Sethi SK, Huang P, Chen S, Yan F, Haacke EM. Regional high iron in the substantia nigra differentiates Parkinson's disease patients from healthy controls. Front Aging Neurosci. 2019:27:11:106. eCollection 2019.  PMID: 31191294. READ PUBLICATION