Günter P. Wagner, Ph.D., N.A.S.

Academic Affiliations
  • Alison Richard Professor of Ecology and Evolutionary Biology, Yale University
  • Adjunct Professor of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine
  • Adjunct Professor – Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Wayne State University School of Medicine, and the Perinatology Research Branch, NICHD/NIH/DHHS
  • Biochemistry, College of Chemical Engineering, University of Vienna
  • Study of Zoology and Mathematical Logics, University of Vienna
  • Postdoctoral Training – Max Planck Institute for Biophysical Chemistry, Göttingen, Germany
  • Postdoctoral Training – Department of Anatomy, University of Göttingen
  • Postdoctoral Training – Max Planck Institute for Developmental Biology, Tübingen, Germany
    Research Accomplishments
    • Discovered transcription factor evolution though altered allosteric effects.
    • Discovered the inflammatory reaction to embryo attachment in opossum, a likely homolog to the inflammatory phase of embryo implantation in placental mammals.
    • Homology, Genes and Evolutionary Innovation (2014) Princeton University Press [winner of the Daniel Giraud Elliot Medal from the National Academy of Sciences].
    Research Interests
    • Evolution of female reproductive biology of mammals
    • Evolution of cell types
    • Evolution of gene regulation: transcription factor protein evolution, the role of transposable elements in gene regulatory network evolution
    Select Publications
    • Griffith OW, Chavan AR, Protopapas S, Maziarz J, Romero R, Wagner GP. Embryo implantation evolved from an ancestral inflammatory attachment reaction. Proc Natl Acad Sci U S A. 2017 Aug 8; 114:E6566-E6575. PMID: 28747528
    • Emera D, Romero R, Wagner G. The evolution of menstruation: a new model for genetic assimilation: explaining molecular origins of maternal responses to fetal invasiveness. Bioessays. 2012 Jan; 34:26-35. PMID: 22057551
    • Lynch VJ, May G, Wagner GP. Regulatory evolution through divergence of a phosphoswitch in the transcription factor CEBPB. Nature. 2011 Nov 13; 480:383-386. PMID: 22080951


    • Comparative Developmental Anatomy of Vertebrates