Prenatal maternal stress causes preterm birth and affects neonatal adaptive immunity in mice

Garcia-Flores V, Romero R, Furcron AE, Levenson D, Galaz J, Zou C, Hassan SS, Hsu CD, Olson D, Metz G, Gomez-Lopez N.
Front Immunol. 2020 Feb 26;11(254). doi: 10.3389/fimmu.2020.00254.

Maternal stress is a well-established risk factor for preterm birth and has been associated with adverse neonatal outcomes in the first and subsequent generations, including increased susceptibility to disease and lasting immunological changes. These findings provide evidence that prenatal maternal stress causes preterm birth and affects neonatal immunity across generations, adverse effects that can be ameliorated upon cessation.


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