Academic Affiliations

Assistant Professor (Research)

  • Department of Obstetrics and Gynecology
    Wayne State University School of Medicine
  • B.Sc. – Chemistry, Microbiology and Parasitology, National School of Biological Sciences, Instituto Politécnico Nacional, Mexico City, Mexico
  • M.Sc. – Molecular Biology and Genetics, The Center for Research and Advanced Studies (CINVESTAV), Mexico City, Mexico
  • Ph.D. – Molecular Biology and Genetics, The Center for Research and Advanced Studies (CINVESTAV), Mexico City, Mexico
  • Fellowship – Wayne State University School of Medicine, Perinatology Research Branch, NICHD/NIH/DHHS, Detroit, Michigan
  • Postgraduate Training: Embryo Transfer, University of Michigan, Ann Arbor, Michigan
  • Postgraduate Training: MAGPIX® System and Real-time Polymerase Chain Reaction (PCR), Life Technologies, Mexico City, Mexico
  • Internship – Immunology, Biomedical Institute of Universidad Autónoma de México (UNAM), Mexico City, Mexico
      Research Interests
      • Cellular and molecular mechanisms involved in preterm birth
      • Develop therapeutic strategies to prevent adverse neonatal outcomes
        Awards & Recognition
        • 2019 Dr. John Gusdon Memorial New Investigator Award – 2nd Place
          Presented at the 39th Annual Meeting of the American Society for Reproductive Immunology Grand Rapids, Michigan
        Select Publications
        • Garcia-Flores V, Romero R, Furcron AE, Levenson D, Galaz J, Zou C, Hassan SS, Hsu CD, Olson D, Metz GAS, Gomez-Lopez N. Prenatal maternal stress causes preterm birth and affects neonatal adaptive immunity in mice. Front Immunol. 2020 Feb 26; 11:254. PMID: 32174914
        • Garcia-Flores V, Romero R, Miller D, Xu Y, Done B, Veerapaneni C, Leng Y, Arenas-Hernandez M, Khan N, Panaitescu B, Hassan SS, Alvarez-Salas LM, Gomez-Lopez N. Inflammation-induced adverse pregnancy and neonatal outcomes can be improved by the immunomodulatory peptide exendin-4. Front Immunol. 2018 Jun 18; 9:1291. PMID: 29967606
        • Theis KR, Romero R, Greenberg JM, Winters AD, Garcia-Flores V, Motomura K, Ahmad MM, Galaz J, Arenas-Hernandez M, Gomez-Lopez N. No consistent evidence for microbiota in murine placental and fetal tissues. mSphere. 2020 Feb 26; 5:pii:e00933-19. PMID: 32102944
        • Pique-Regi R, Romero R, Tarca AL, Sendler ED, Xu Y, Garcia-Flores V, Leng Y, Luca F, Hassan SS, Gomez-Lopez N. Single cell transcriptional signatures of the human placenta in term and preterm parturition. eLIFE. 2019 Dec 12; 8:pii:e52004. PMID: 31829938
        • Gomez-Lopez N, Motomura K, Miller D, Garcia-Flores V, Galaz J, Romero R. Inflammasomes: their role in normal and complicated pregnancies. J Immunol. 2019 Dec 1; 203:2757-2769. Review. PMID: 31740550
        • Gomez-Lopez N, Romero R, Xu Y, Miller D, Arenas-Hernandez M, Garcia-Flores V, Panaitescu B, Galaz J, Hsu CD, Para R, Berry SM. Fetal T cell activation in the amniotic cavity during preterm labor: a potential mechanism for a subset of idiopathic preterm birth. J Immunol. 2019 Oct 1; 203:1793-1807. PMID: 31492740
        • Arenas-Hernandez M, Romero R, Xu Y, Panaitescu B, Garcia-Flores V, Miller D, Ahn H, Done B, Hassan SS, Hsu CD, Tarca AL, Sanchez-Torres C, Gomez-Lopez N. Effector and activated T cells induce preterm labor and birth that is prevented by treatment with progesterone. J Immunol. 2019 May 1; 202:2585-2608. PMID: 30918041
        • Gomez-Lopez N, Romero R, Garcia-Flores V, Leng Y, Miller D, Hassan SS, Hsu CD, Panaitescu B. Inhibition of the NLRP3 inflammasome can prevent sterile intra-amniotic inflammation, preterm labor/birth, and adverse neonatal outcomes. Biol Reprod. 2019 May 1; 100:1306-1318. PMID: 30596885
        • Miller D, Motomura K, Garcia-Flores V, Romero R, Gomez-Lopez N. Innate lymphoid cells in the maternal and fetal compartments. Front Immunol. 2018 Oct 26; 9:2396. Review. PMID: 30416502
        • Gomez-Lopez N, Romero R, Arenas-Hernandez M, Panaitescu B, Garcia-Flores V, Mial TN, Sahi A, Hassan SS. Intra-amniotic administration of lipopolysaccharide induces spontaneous preterm labor and birth in the absence of a body temperature change. J Matern Fetal Neonatal Med. 2018 Feb; 31:439-446. PMID: 28139962
        • Gomez-Lopez N, Romero R, Garcia-Flores V, Xu Y, Leng Y, Alhousseini A, Hassan SS, Panaitescu B. Amniotic fluid neutrophils can phagocytize bacteria: A mechanism for microbial killing in the amniotic cavity. Am J Reprod Immunol. 2017 Oct; 78:12723. PMID: 28703488
        • Xu Y, Romero R, Miller D, Kadam L, Mial TN, Plazyo O, Garcia-Flores V, Hassan SS, Xu Z, Tarca AL, Drewlo S, Gomez-Lopez N. An M1-like macrophage polarization in decidual tissue during spontaneous preterm labor that is attenuated by rosiglitazone treatment. J Immunol. 2016 Mar 15; 196:2476-2491. PMID: 26889045